Stem Cell Therapy for Retinopathy of Prematurity

refractive errors after laser therapy for retinopathy of prematurity

purpose: retinopathy of prematurity (rop) adversely affects normal ocular vascularization in premature infants. it can be mild with no visual consequences, or may become aggressive with new vessel formation and even progress to retinal detachment and blindness. modern treatment can prevent blindness due to neovascularization but uncorrected refractive errors may lead to amblyopia. methods: in t...

Hypotension Associated With Intravitreal Bevacizumab Therapy for Retinopathy of Prematurity.

Intravitreal bevacizumab therapy in preterm infants for retinopathy of prematurity (ROP) can be associated with hypotension. We report twin preterm infants who developed hypotension within 1 day after intravitreal bevacizumab therapy for ROP. Before receiving the medication, their clinical statuses were stable and similar. The dose, procedure, and premedication were the same; however, twin B pr...

Vascular endothelial growth factor antagonist therapy for retinopathy of prematurity.

In this article, the growing problem of retinopathy of prematurity (ROP) worldwide, treatments for severe ROP including standard-of-care laser treatment, and the need for new treatments are discussed. Also discussed are the reasons to consider inhibiting the vascular endothelial growth factor (VEGF) signaling pathway in severe ROP and the concerns about broad VEGF inhibition. Finally, the poten...

Circulating stem cell populations in preterm infants: implications for the development of retinopathy of prematurity.

OBJECTIVE To investigate the association among different circulating stem cell (SC) populations, the levels of selected growth factors and chemokines regulating SC migration in the peripheral blood, and the incidence of retinopathy of prematurity (ROP). METHODS We evaluated 88 participants in this study: 29 preterm infants with ROP, 29 preterm infants without ROP, and 30 healthy full-term inf...

Bevacizumab for retinopathy of prematurity.